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Archiv-Übersicht     Angebot Nr. 12552

Angebotsdatum: 8. November 2017
Art der Stelle: Doktorarbeit / Diplomarbeit
Fachgebiet: Biologie > Zellbiologie
Titel des Themas: Human microglia in Parkinson’s disease specific brain organoids.

Institut: LCSB - Luxembourg Centre for Systems Biomedicine
Adresse:
Herr Jens Schwamborn
6, avenue du Swing
4367 Belvaux (Luxembourg)
Tel.:    Fax.:
Bundesland:
Homepage: http://schwambornlab.uni.lu
E-Mail Kontakt: mail

Beschreibung: The Developmental and Cellular Biology Group (led by Prof. Jens Schwamborn) at the Luxembourg Centre for Systems Biomedicine utilizes human stem cells for modeling and experimental treatment of neurodegenerative disease. Projects in the lab are at the interface of systems biology and bio-medical research. In particular we aim on gaining new insights in the complex processes that regulate neuro-degenerative as well as -regenerative processes.
In this project for a PhD student we will use human patient specific iPSCs to derive microglia from them. These disease specific microglia shall be used in our recently published midbrain organoids to develop an advanced in vitro model for Parkinson’s disease. The project combines elements of stem cell research, neurobiology and immunology.
Successful applicants should have a strong interest in Cell Biology and Neurobiology, especially experience in stem cell biology and/or immunology would be a plus. We are looking for highly motivated people who share our passion for research, are interested in acquiring new skills and wish to be part of an international team.
Application
Applications (in English) should contain the following documents:
• A detailed curriculum vitae
• Cover letter
• Description of past research experience and future interests
• Name and addresses of referees

Contact
Prof. Dr. Jens C. Schwamborn
Université du Luxembourg; LCSB - Luxembourg Centre for Systems Biomedicine
Developmental and Cellular Biology
7, Avenue des hauts-fourneaux, L-4362 Esch sur Alzette (Belval)
T. +352 / 4666445536
E. jens.schwamborn@uni.lu
Methoden: iPSC technology
Microglia
Brain Organoids
High content Microscopy
Anfangsdatum: 1. Februar 2018
Geschätzte Dauer: 3 years
Bezahlung:
Papers: http://www.cell.com/stem-cell-reports/abstract/S2213-6711(17)30116-9
Sonstiges:

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