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Archiv-Übersicht     Angebot Nr. 12520

Angebotsdatum: 19. Oktober 2017
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Molekularbiologie
Titel des Themas: Molecular mechanisms of coccolith biomineralization

Institut: Max Planck Institute of Molecular Plant Physiology
Dr. rer. nat. Andre Scheffel
Am Muehlenberg 1
14476 Potsdam
Tel.:    Fax.:
Bundesland: Brandenburg
Homepage: http://www.mpimp-golm.mpg.de/15419/2scheffel
E-Mail Kontakt: mail

Beschreibung: The „Algal Biomineralization“ lab at the Max Planck Institute of Molecular Plant Physiology (Germany) invites applications for a PhD student position to study the formation of the mineralized scales that cover the cells of coccolithophorid algae. These cell coverings are called coccoliths and paradigms for CaCO3 biominerals. Coccolith formation is of great importance in the context of marine ecosystem ecology and climate regulation as well as in context of bioinspired materials synthesis. The project aims for the identification of macromolecules involved in coccolith formation and at understanding their roles in the process.

The project includes aspects of:
• Isolation and characterization (using biochemical, spectroscopy and imaging techniques) of macromolecules (polysaccharides and proteins) involved in coccolith biogenesis
• Functional analysis of isolated macromolecules using in vitro mineralization assays and state-of-the-art analytical techniques
• Identification and cloning of genes involved in coccolith biogenesis
• Genetic engineering of coccolithophorid algae

Applicants with excellent Master/Diploma degree in chemistry, biology, biotechnology or biochemistry and genuine interest in research and experimental enthusiasm are strongly encouraged to apply. Experience with molecular biology and biochemical techniques is an asset.

For further information please visit the labs website (www.mpimp-golm.mpg.de/15419/2scheffel) or contact Dr. Scheffel.

Interested candidates should send a single PDF file including curriculum vitae, motivation letter, copies of most recent diplomas, and contact details of minimum two referees by e-mail to Dr. André Scheffel (Scheffel@mpimp-golm.mpg.de). The starting date is negotiable but the position is available from January 2018 for three years. Applications will be considered until the position is filled.
Anfangsdatum: 1. Januar 2018
Geschätzte Dauer: 3 Jahre
Papers: Gal A., Wirth R., Kopka J., Fratzl P., Faivre D. and Scheffel A. (2016) Macromolecular recognition directs calcium ions to coccolith mineralization sites. Science 353: 590-593

Skeffington A.W. and Scheffel A. (2017) Exploiting algal mineralization for nanotechnology: Bringing coccoliths to the fore. Curr. Opin. Biotechnol. 49: 57-63